jar

A mouse brain in a jar, trading stock tokens on Robinhood Chain. Its neurons, their shapes and every connection between them are real, taken from one mouse's visual cortex as mapped in MICrONS, Nature 2025.

Opening the jar.

72 of the neurons, one per row. Every dot is a spike. A cursor sweeps left to right, writing each new tenth of a second over the oldest column. The top rows are voters, and they turn orange while their stock is being heard.

Hover a neuron to see what it is.

What it is doing

$10,000.00

Paper money. It started with $10,000.

stocksharesvaluesince bought
Nothing held yet.
logconnecting

    The rule

    stockpricewiringfull risefull falllast call

    Wiring counts synapses from a stock's input cells to its output cells, directly and through one excitatory cell. Full rise and full fall are how many times the usual output a 0.5% move produced when we ran the simulation for a minute each.

    What is real and what is ours

    Real. 1,627 neurons from the MICrONS cubic millimetre of mouse visual cortex: their reconstructed shapes, cell types, positions, and the 52,181 connections between them. The brain around them is the adult mouse outline from the DevCCF atlas. Prices are Chainlink feeds on Robinhood Chain.

    Ours. The neuron model: leaky integrate-and-fire, with constants from a whole-brain fly model, and each connection made stronger than life because we only see a few dozen of each cell's thousands of inputs. Which cells hear prices, which ones vote, and the rule. The cube's place in the brain, which is approximate: the two datasets come from different mice and are not registered to each other. And the money, which is paper. There is no wallet and no real order.

    Papers

    1. The MICrONS Consortium. Functional connectomics spanning multiple areas of mouse visual cortex. Nature 640, 435–447 (2025). doi:10.1038/s41586-025-08790-w. The neurons, their shapes and their connections. Skeletons from microns-explorer.org (v1300 proofread set); connectivity from the v117 release packaged on Zenodo 8364070. CC BY 4.0.
    2. Kronman, F. N. et al. Developmental mouse brain common coordinate framework. Nature Communications 15, 9072 (2024). doi:10.1038/s41467-024-53254-w. The brain outline and the occipital cortex patch, from the P56 adult template. CC BY 4.0.
    3. Shiu, P. K., Sterne, G. R. et al. A Drosophila computational brain model reveals sensorimotor processing. Nature 634, 210–219 (2024). doi:10.1038/s41586-024-07763-9. The leaky integrate-and-fire constants: 20 ms membrane, 5 ms synapse, rest and reset at −52 mV, threshold −45 mV, 2.2 ms refractory.